A bipartisan initiative in the U.S. House of Representatives to modernize the drug development and approval system held the first in a series of exploratory hearings today. The so-called 21st Century Cures initiative, launched by two senior lawmakers on 30 April, will spend several months soliciting feedback from scientists, regulators, patients, and industry experts. The lawmakers may then propose legislation aimed at more quickly moving potential treatments from the lab to the clinic.The initiative is the result of collaboration between Representative Fred Upton (R–MI), the chair of the Energy and Commerce Committee, and Representative Diana DeGette (D–CO), one of the panel’s senior Democrats. In an online announcement of the effort, the pair expressed concern that getting drugs to market is increasingly costly and time-consuming. Upton lamented “a major gap between the science of cures and the way we regulate these therapies,” and DeGette, an outspoken supporter of human embryonic stem cell research, vowed to “take a comprehensive look” at how Congress might intervene. Upton, a conservative who often parts company with DeGette on policy issues, wrote in a recent U.S. News and World Report op-ed that “U.S. regulatory policies remain stuck in the Sgt. Pepper era.” Upton is in a powerful position to act on these concerns. He has at least 2.5 years remaining as chair of his committee, which helps oversee the Department of Health and Human Services and the Food and Drug Administration (FDA), among other agencies.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)On 6 May, the pair kicked off the initiative by hosting an informal round table. Guests included National Institutes of Health Director Francis Collins and Janet Woodcock, the director of FDA’s Center for Drug Evaluation and Research. They discussed what are likely to be recurring buzzwords in the ongoing conversation: promoting “clinical trial networks” that could oversee multiple drug trials; identifying “surrogate endpoints” for clinical trials—short-term markers that a patient is benefiting from a drug that might speed its approval; and encouraging FDA to make broader use of its “accelerated approval” pathway, historically limited mostly to approving cancer and HIV treatments.At today’s health subcommittee hearing, the experts invited to testify echoed many of those suggestions. The panel included five contributors to a President’s Council of Advisors on Science and Technology report on drug innovation, which in 2012 offered a list of recommendations for improving the drug approval process. Sara Radcliffe, executive vice president for health at the Biotechnology Industry Organization, said she’d like FDA to further clarify how a drug trial might introduce a new endpoint to measure its efficacy, and how medicines targeted at small populations might better take advantage of the expedited approval process that already exists. Frank Sasinowski, speaking on behalf of the National Organization for Rare Disorders, repeated that suggestion. Questions from committee members also focused largely on FDA, and many were critical of what they perceived as a risk-averse culture at the agency.The emphasis on FDA reflects an area where the committee has focused its legislative energies in the past, Jeff Allen, one of the witnesses at the hearing and executive director of Friends of Cancer Research in Washington, D.C., told ScienceInsider. He noted that the panel played a big role in shepherding into law a 2012 measure—the FDA Safety and Innovation Act (FDASIA)—which created a new “breakthrough therapy” designation to speed the approval process for certain treatments for seriously ill patients. The new effort is a way to look beyond FDASIA, he believes. “That law was squarely focused on the FDA, and perhaps the 21st Century Cures [initiative] will allow an examination of the totality of the system, rather than just the point of market entry.”Press releases and white papers from the initiative hint that it might take a more holistic view. The most recent, for instance, asks patients to send the panel comments on the current state of research, funding, and available treatment for their diseases.Not surprisingly, many researchers and patient groups watching the new initiative say funding for basic research that identifies new drug targets is a key issue. But spending levels aren’t something that Upton’s committee controls; that’s largely up to the appropriations panels. Still, Radcliffe told ScienceInsider that although today’s hearing produced nothing she hasn’t heard before, there were “some really interesting proposals.” It will likely be many months, however, before advocates learn how Upton and DeGette plan to respond to what they learn.
Mumbai, Apr 7 (PTI) IndusInd Bank today announced its support to the Indian para athletes, who qualify for this years Rio Paralympics, through its Para Champions Programme — IndusInd Umang — designed for differently-abled sportspersons. Fifteen emerging and elite para athletes have been selected to receive support under the programme in the first year with two among them — Amit Saroha and Devendra Jhajharia — having already qualified for the Paralympic Games in Rio de Janeiro in Brazil this September, a media release said today. Para swimmer Suyash Jadhav, also among 15 athletes, has already breached the A qualification mark for the Paralympics this year. The programme is in association with GoSports Foundation, an independent, professionally-managed and donor-funded organisation focused on promoting sports in the country with an advisory board comprising sporting icons Abhinav Bindra, Rahul Dravid and Pullela Gopichand. “The programme seeks to impact the lives of the selected 15 athletes positively, and boost them to the next level in their sporting journeys,” the release said. This is the first time a cohesive and comprehensive programme and commitment have been put in place for para athletes by any corporate in the country, it added. PTI SSR KRK CM AH
The Indian U-17 football team played out a 1-1 draw against French club FC Saint Leu here on Wednesday.The match against the second division side of the Paris League was part of the exposure trip of Europe for the Indian boys who will take part in the U-17 World Cup in India later this year.In a drab first half that ended with both the teams going back to the dressing room level, the Indians dominated possession but lacked the necessary firepower upfront to take the lead.In the 28th minute, Shubham’s shot was saved by the opposition goalkeeper after he latched onto a through pass by Shahajahan.Boris proved to be a threat on the flanks but his crosses in the box failed to find the Indian forwards upfront.However, in the 58th minute, the French boys took the lead after Remi found the net following up on Dheeraj’s faulty clearance.In the 72nd minute, Komal put India back on level terms after he latched onto a long goal-kick and scored to make it 1-1.72′ GOAL! Komal puts the ball in and equalizes proceedings. #BackTheBlue #ColtsInEurope- Indian Football Team (@IndianFootball) May 16, 2017
All India Football Federation (AIFF) has honoured football team captain Sunil Chhetri with the 2017 Player of the Year award. Kamala Devi was adjudged the 2017 AIFF woman Player of the Year.Chhetri is currently the third highest goalscorer among active footballers in the world with 64 goals. Chhetri reached the 64-goal mark in 102 international games and for a brief period shared the second spot with Lionel Messi until Argentine scored against Nigeria in the FIFA World Cup 2018 in Russia.Besides recently becoming the second Indian to play 100 international games after former star striker Baichung Bhutia, Chhetri is also the skipper of former I-League champions and current Super Cup holders Bengaluru FC.Meanwhile, Anirudh Thapa was declared the 2017 Emerging Player of the Year.E. Panthoi is the 2017 woman Emerging Player of the Year, the AIFF said in a statement.The award for best grassroots development programme went to the state association of Kerala.Hero Motocorp which sponsors the I-League, Indian Super League and the newly launched Super Cup, took home the AIFF Award for long-time contribution to Indian football.Sumanta Datta of Assam was named the best assistant referee while the award for best referee went to C.R. Srikrishna.2017 AIFF Award winners:2017 AIFF Award for Best Grassroots Development Programme: Kerala FA2017 AIFF Award for long-time contribution to Indian Football: Hero Motocorp2017 AIFF Award for Best Assistant Referee: Sumanta Datta (Assam)2017 AIFF Award for Best Referee: C R Srikrishna2017 AIFF Emerging Woman Footballer of the Year: E Panthoi2017 AIFF Emerging Player of the Year: Anirudh Thapaadvertisement2017 AIFF Woman Footballer of the Year: Kamala Devi2017 AIFF Player of the Year: Sunil Chhetri
Nova Scotians are invited to comment on a report released today,Dec. 2, on the province’s emergency response to Hurricane Juan. The report is a summary of the debriefing that took place at theEmergency Measures Organization(EMO) on Oct. 29, 2003. EMO holdsa debriefing after every major emergency to determine how theresponse was handled and identify areas of improvements. “I am very proud of the co-ordinated effort that responded to thehurricane, which I believe helped foster a sense of stability andoptimism among Nova Scotians,” said Ernest Fage, Ministerresponsible for the Emergency Measures Act. “No matter how good aresponse is, we can always learn from our experience. We haveheard from the agencies involved in the response and now we areasking Nova Scotians for their comments.” The report describes the overall response effort by focusing ontwo key topics: the breadth, scope, strengths and weaknesses ofthe emergency response effort; and the lessons learned as aresult of that effort. Recommendations centre around three mainareas: improved use of resources and people, improved operationalprotocols and improved communications. The summary report and the verbatim account of the debriefing canbe found on EMO’s website at http://www.gov.ns.ca/emo . Copies of thesummary report are available at all Access Nova Scotia Centresacross the province. Nova Scotians can comment on the emergency response by e-mail firstname.lastname@example.org, by mail to Response to Hurricane Juan,P.O. Box 608, Halifax, NS, B3J 2R7, or by calling 424-7609 or 1-800-607-5565 before Dec. 31, 2003. Comments will be compiled and reported back to the ProvincialEmergency Activation Team. EMERGENCY MEASURES ORGANIZATION–Report on Emergency Response toHurricane Juan
TORONTO – Legal actions against the Soulpepper Theatre Company and its co-founder, Albert Schultz, over sexual-harassment allegations have been “resolved,” representatives said Wednesday.A lawyer representing Schultz tells The Canadian Press that lawsuits alleging he sexually harassed multiple actresses have been settled in a way that is “satisfactory” to his client. Peter Wardle declined a request for further comment.A Soulpepper spokesperson confirmed that the legal actions had been resolved, saying the past several months have been a “challenging” period for the Toronto non-profit theatre.“We are committed to continuing our process of renewal,” Brad Lepp said in a statement.“We are focused on ensuring not only that our policies are as strong as possible, but also that the structure and culture create a safe and respectful environment that supports all our artists and staff while maintaining the highest level of excellence in all that we do.”A lawyer for the four actresses who sued Schultz and Soulpepper said her clients had no comment beyond confirming that the “matters have settled.”In statements of claim filed in Ontario Superior Court in January, the women alleged that Schultz groped them, exposed himself, pressed against them or otherwise behaved inappropriately.Schultz resigned hours after Kristin Booth, Hannah Miller, Diana Bentley and Patricia Fagan held a news conference to lambast him and Soulpepper.They alleged that Soulpepper created a culture where it was difficult to make a complaint and those that did were either ignored or punished.At the time, Schultz said he would vigorously defend himself against the allegations. Both he and Soulpepper did file notices of intent to defend in the case.The scandal also prompted Soulpepper to part ways with Leslie Lester, Schultz’s wife and the company’s executive director.The theatre company had said it was unaware of any misconduct allegations against Schultz or anyone else, having investigated as recently as the fall of 2017.Soulpepper bills itself as Toronto’s largest not-for-profit theatre company and Schultz played a key role in its repertoire.Last month, acting artistic director Alan Dilworth said Soulpepper was in the midst of a “culture change,” and announced the company would put its prestigious training academy on a one-year hold to do a review before admitting a new troupe of artists.Nearly $2.4 million has been allocated to Soulpepper under various Canadian Heritage programs since the early 2000s, according to a February briefing note prepared for former heritage minister Melanie Joly.This funding is separate to the roughly $185,000 a year that Soulpepper has received from the Canada Council for the Arts in the past.In February, the arms-length Crown corporation said it was rescinding a planned funding increase for Soulpepper, but would maintain its base funding.After reporting a $556,000 deficit for 2017, Dilworth has said Soulpepper is projecting further losses this year, but that he expected the non-profit will be in the black within two years.
Best-selling author, philanthropist, educator and former First Lady of the United States Laura Bush will speak at the 2018 NAFSA Annual Conference & Expo in Philadelphia, Pennsylvania.Mrs. Bush is a powerful advocate for literacy, education and human rights, and she will address the conference on Tuesday, May 29.As First Lady, Mrs. Bush advocated for the importance of literacy and education to advance opportunity for America’s young people and to foster healthy families and communities. She highlighted the importance of preparing children to become lifelong learners, convening in 2001 a White House Summit on Early Childhood Cognitive Development and creating the National Book Festival in Washington, D.C.Today, as Chair of the Bush Institute’s Women’s Initiative, Mrs. Bush promotes access to education, healthcare and economic opportunity for women and girls around the world. The Women’s Initiative programs are preparing and empowering the next generation of women leaders in North Africa and the Middle East, working to ensure the expansion and protection of women’s rights in Afghanistan and engaging and supporting First Ladies from around the world to effectively use their unique platforms to advance issues for women and girls in their countries.“Through her early work as an educator, her years in the White House and now as a leader at the Bush Institute, Mrs. Bush demonstrates the impact passionate advocates can make throughout all sectors of society,” commented Esther D. Brimmer, NAFSA Executive Director and CEO. “As a strong advocate for literacy, education and human rights around the world, her contributions to the NAFSA conference will no doubt serve as a catalyst for vital discussion and engagement among our attendees.”Mrs. Bush is the author of the bestselling memoir, Spoken From the Heart, and bestselling children’s book, Our Great Big Backyard. She also wrote the forward to We Are Afghan Women: Voices of Hope. Born in Midland, Texas, she holds a Bachelor of Science degree in education from Southern Methodist University and a master’s degree in library science from the University of Texas.This plenary session featuring Mrs. Bush is sponsored in part by Education in Ireland. Learn more about all the plenary speakers here.
Godfrey is a great comic, especially familiar to those in the New York comedy scene, who has previously recorded specials with Comedy Central and Showtime and appeared in films like Zoolander and Johnson Family Vacation.by Bill Tressler – The Interro Bang Login/Register With: Advertisement Advertisement SiriusXM announced on Thursday that comedian Godfrey (Steven Universe, Soul Plane) will be hosting a new one-hour talk show on Urban View channel 126 called The Power Hour starting on Monday, July 31st. The new show will feature the comic using his laid-back, thoughtful style to tackle everything from rap and race issues to politics and current events, supplemented by interviews with musicians, authors and politicians.“I can’t wait to get behind the mic and have honest, open conversations with SiriusXM listeners and guests about what’s really on our minds,” said Godfrey of the new show. “I’m not interested in being politically correct; I’m interested in moving towards a place where we can be real and have transparent discussions that entertain and move us all forward.”“Godfrey is a true, indefatigable talent and we are thrilled to announce the launch of The Power Hour on Urban View,” said Karen Hunter, Urban View host and Programming Consultant. “Godfrey’s humor and ability to approach the difficult issues most people shy away from with ease is sure to make The Power Hour a listener favorite.” Facebook Advertisement LEAVE A REPLY Cancel replyLog in to leave a comment Twitter
TORONTO — Shares of Barrick Gold Corp. slipped Wednesday after the Canadian mining giant suffered a legal reversal that may affect development of the company’s Pascua Lama project on the border between Argentina and Chile.The company’s stock closed down 63 cents at $38.87 on the Toronto Stock Exchange.Argentina’s Supreme Court decided Tuesday to remove injunctions that have blocked key parts of a law to protect glaciers. Barrick argued it shouldn’t need to provide the national government with new environmental assessments.[np-related]The law requires a thorough inventory of Argentina’s glaciers as well as “periglacial” areas where the ice has recently retreated but water remains below the surface. Together, the areas provide much of the country’s fresh water.The law also gives the national government a powerful tool to regulate the mining industry, which until now has been handled by provincial governments whose priorities sometimes clash with people living downstream from the mines.Barrick maintains that it does not mine on glaciers and that it has already persuaded the provinces it will contain any environmental damage from gold mining, which requires lots of fresh water and a mix of toxic chemicals.The ruling Tuesday could have a major impact on Pascua Lama, the world’s highest-altitude gold mine being developed on both sides of the Chile-Argentine border. Barrick said the $5-billion project already has found nearly 18 million ounces of proven gold reserves, more than the company’s Veladero mine, another open-pit mine nearby that is already in production.Groups including Greenpeace Argentina and the Foundation for Environmental and Natural Resources cheered the ruling as a key step. The high court has yet to decide the constitutionality of the overall law, or rule on the environmentalists’ requests for an immediate halt to Barrick’s high-altitude mining.In asking for an injunction against several aspects of the law Barrick said enforcing the measures would unfairly “create a state of uneasiness and uncertainty” surrounding its operations.“The Supreme Court must still rule on the constitutionality of the law, which has been challenged by the province of San Juan, labour unions and the mining industry,” Barrick said in a statement.“The federal legislation also draws a distinction between new projects, and those already underway. Our Veladero mine has been in operation since 2005 and construction at Pascua-Lama has been underway since 2009.”The parts of the law Barrick objected to require the national government to define what a glacier is, inventory the remaining glacial and periglacial areas in Argentina, prohibit any activities that destroy glaciers, ban mining in glacial and periglacial areas, and require companies to provide environmental impact statements at the national level.Rulings by lower courts that blocked those measures were fundamentally flawed, because the requirements provide for the very certainty that Barrick Gold claims it wants, the Supreme Court justices said. The glacier inventory “will make known exactly which areas are protected by law,” they wrote.Barrick and other mining companies as well as the mountainous provinces that directly benefit from their control of the industry have challenged the law on constitutional grounds, saying the national government should have no role in regulating mining. But the justices said that “the law must be applied its constitutional validity is resolved.”
Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)RelatedGDF Captain accused of murder further remandedMay 2, 2018In “Court”GDF Captain remanded for murdering loverApril 6, 2018In “Court”GDF Captain to be arraigned tomorrow for murder of girlfriendApril 3, 2018In “Crime” The interdicted Guyana Defence Force (GDF) Captain Orwain Sandy, who is accused of murdering his reputed wife Reona Payne last month in Alexander Village, Georgetown, was on Tuesday morning remanded to prison for the second time, as his murder trial continued.Accused: Orwain SandyAccording to the prosecution, the investigations regarding the case are still incomplete, and the psychiatric evaluation report which was ordered during Sandy’s arraignment is still being awaited.As such, the Prosecution requested additional time.City Magistrate Judy Latchman adjourned the matter for May 2, 2018 when the psychiatric report is expected to be presented to the Court.Outside of the Courtroom, friends, and family members along with Payne’s three children were seen wearing t-shirts with her picture calling for justice for the dead woman.INews had reported that March 31, 2018, Sandy allegedly killed his lover, Reona Payne by shooting her about her body 14 times.According to eyewitness reports, the couple were in their car proceeding along First Street, Alexander Village when a heated argument reportedly ensued.As such, Payne reportedly exited the vehicle after which Sandy followed, carrying a loaded firearm.He allegedly shot the woman once, resulting in her dropping to the ground, then stood over her and emptied the entire magazine.The Captain then fled the scene and turned himself over at the Ruimveldt Police Station, where he reported the matter.The police were also summoned by residents who heard the gunshots.When INews visited the scene, the woman’s lifeless body was found on the road along with several spent shells which were recovered by the police.Following the incident, Sandy was ‘was immediately interdicted from his duties,’ a statement from GDF said.This online publication understands that Payne and Sandy had been together for quite some time. However, a few years back, the duo split and married different people.After a while, they both reportedly gave up on their marriages and made their way back to each other.
When the guy told me, I stopped the car to see. My colleague and I found that a dog was still alive.The dog – since renamed Victory – had broken through the bumper and was lodged inside it. She was taken to a clinic for treatment, where vet Lorena de Oliveira Figueira described her as “blessed by God”.Victory is now seeking a new adoptive family.Fan granted iTunes refund on ‘homophobic’ James Arthur album>Guy makes Beastie Boys music video while on holidays with his mam> A VERY LUCKY dog has survived a 90km journey hanging from a car bumper after being hit by a driver in Brazil.The female animal – who came through the ordeal with just a broken leg – is now looking for a new adoptive home.Driver Julius Caesar Smith, 35, struck the dog in the Itapetinga area earlier this week. He told G1 Globo that he noticed the bump, but did not stop as it was on a dangerous series of bends and he assumed the dog was dead.Some 90km later, Smith was signalled by another driver that there was something lodged in the bumper of his car. He said:
Nvidia’s big reveal at CES this year was the Tegra 4 platform, as well as the first piece of hardware to run it. While the Project Shield looks exciting, rather than plugging it in to a television to get the full affect of the console, what if you could connect it to the Oculus Rift gaming headset?From the HDMI port on the back of the Shield unit to the converter for Oculus Rift and then straight into your eyeballs — you couldn’t possibly go wrong with a combination like that. As Project Shield promises access to the best of gaming on the Google Play Store as well as the Steam Store and other PC titles, thanks to Nvidia’s new streaming tech.We also know that Valve has been working with Oculus Rift for some time in order to get their games ready to enjoy on the headset, and the Oculus team themselves have been working on their own libraries for most of the popular gaming languages. On paper, it seems like this could be a really great combination.The Oculus Rift experience is demanding to say the least. In order to maintain the illusion that you are fully immersed in the world you are playing in, the hardware pushing pixels to your eyeballs can’t dip below 60 fps. In the demonstration provided to us by the Oculus team during CES, the experience is really jarring when the frames start to drop. Imagine that sensation you feel when you are listening to a song and half way through the audio stops for no reason. Dropping frames while wearing Rift offers that sensation, but for your eyes. When your whole world goes black for no reason, you want that to stop pretty quickly.So if this was to work, Project Shield would need to be powerful enough to drive the Rift at 60 fps consistently both through native gameplay and while streaming gameplay from your PC.What we’ve heard and seen from Project Shield so far is impressive for a mobile console, but how does that stack up against discrete graphics on a PC? The quad-core-with-a-companion-core architecture of the Tegra 4 is impressive, though for now there’s been little mention of the clock speed for this version of the chipset. Surrounding this CPU is 72 “cores,” though that word doesn’t quite mean the same thing as the GPU cores you’d find in a regular PC graphics card. The reality is that the cores in the Tegra 4 GPU are stream processors that perform smaller, simpler operations for the GPU. That’s more than enough power, right?In order to do what we want here, this chipset would need to output 1280×800 split into a pair of 640×800 screens, both of which run at 60 fps even when under stress. We know the hardware can output video at a much higher resolution than this, given the ability to display 4K content at 24FPS, so it seems like the Tegra 4 platform would be able to handle this fairly well.Hardware is not enough, though, as you’d need Android game developers to support the hardware. The amount of work that has gone into things like the Unity demo for Rift so far demonstrates a totally different approach to gameplay. Designing a game in 3D requires the game to be rendered completely, instead of just what the user can see when looking straight ahead. If you look up at a tree when wearing Rift and you see 2D branches in a crosshatch pattern because that’s all you need to get away with a 3D looking tree on a flat screen, Rift users will notice immediately.In order for game developers on Android to support the Rift, the games themselves would need a lot of changes to look nice on the headset. It’s certainly possible that a high volume of users will encourage developers to enhance their apps, but at least in the beginning the number of users who own both Project Shield and Oculus Rift will be a small demographic.In the end, this isn’t as much of a pipe dream as it seems, but there are a number of challenges in between the users and the experience that could make the reality of this happening fairly slim. Perhaps if Nvidia and Oculus were to collaborate directly, this could happen much faster. In the mean time, you could sit at your desk with your eyes closed and imagine your friends and family never seeing you without a Rift on your face and a controller in your hands again.Read more: Hands on the Oculus Rift VR headset
Pinterest Facebook Google+ Disney CEO Bob Iger Leaves Apple’s Board Of Directors Now Playing Up Next WhatsApp Insight Editions announces “WWE: The Official Cookbook” set for release on March 19 Now Playing Up Next Now Playing Up Next SPOILERS: 3/22 and 3/23 Impact TV taping results from Windsor, Ontario, Canada Now Playing Up Next Roku Aims To Beat Netflix In European Streaming Market Apple TV+ To Be Offered For $4.99 Per Month The Tech Behind the First FDA-Approved Birth Control App Now Playing Up Next Trade hopes lift Wall Street Jason Namako RELATED ARTICLESMORE FROM AUTHOR Twitter Match announced for next week’s 205 Live, 8-Man Elimination from TLC PPV in 2015 OSN announced yesterday that the WWE Network has officially announced in the Middle East & Northern Africa. It is available for free to all OSN subscribers for the first seven days, beginning yesterday (3/22) online and as a linear cable channel. On Sunday (3/29), the day of Wrestlemania 31, it will be made available for free for all OSN subscribers who have their Platinum tier package and $9.99 a month for all other OSN subscriber packages. OSN.com: What’s New – OSN WWE Network HDRecommended videosPowered by AnyClipApple TV+ To Be Offered For $4.99 Per MonthVideo Player is loading.Play VideoPauseUnmuteDuration 0:32/Current Time 0:05Loaded: 100.00%0:05Remaining Time -0:27 FullscreenUp NextThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.Replay the list
Related Items:five cays, Pdm, premier rufus ewing, sean astwood TCI Premier blasts Opposition side for “slop” information, sets it straight in HOA Only Doug and Ralph and Ruth can fit, that’s why Facebook Twitter Google+LinkedInPinterestWhatsAppProvidenciales, 17 Dec 2014 – The Premier is not being proactive enough about the so called, ‘sluggish processing’of the Crown Land Unit application of the resort development project touted for Five Cays. It was during the PDM Party’s mid-term report card press Conference, that shadow minister for business in the Opposition Party and Member for Five Cays, Hon Sean Astwood explained the problems and the TC Weekly news quotes him saying: “I do know that government departments that have responsibility of facilitating this development need to get their act together.” As for what the Member feels is at stake here, everything. “I am afraid that if that doesn’t happen soon the developers might look somewhere else to do their project.” Cabinet has already approved and bragged about the development; five months later the eco-adventure, low density, spa resort project remains in limbo because of bureaucracy. Recommended for you TCI Country Leaders condemn vicious memes Facebook Twitter Google+LinkedInPinterestWhatsApp
Dan Cohen AUTHOR DOD’s program for supporting communities coping with the cancellation of a defense contract or a major reduction in defense spending would be eliminated under the fiscal 2016 defense authorization bill approved by the Senate Armed Services Committee on May 14.The committee calls for stripping out $33.1 million from the Pentagon’s $110.6 million FY 2016 budget request for the Office of Economic Adjustment (OEA) that would fund the agency’s defense industry adjustment program. The committee also recommended stripping out $20.0 million from the request for civilian water and wastewater infrastructure improvements needed on Guam to accommodate an influx of Marines.The version of the defense authorization bill passed by the House on May 15 leaves the $110.6 million request for OEA intact, so the discrepancy will need to be hashed out in conference after the Senate takes up its version on the chamber floor.The Senate Armed Services Committee said very little in its report accompanying the authorization bill to justify slashing OEA funding by a total of $53.1 million other than stating that it “believes this funding should be realigned to support high priority readiness and modernization requirements.”OEA’s defense industry adjustment program helps states and local governments respond to reductions in defense industry employment by planning and carrying out community adjustments and economic diversification activities. Agency support typically focuses on regional job creation through business development, attraction and expansion, workforce development, and community economic diversification.Congress allocated $281.4 million to OEA for FY 2015, but the extra funds were part of a one-time add-on to address capacity and facility condition deficiencies at public schools on military installations. The agency received $120.5 million in FY 2014.The bill text, S. 1376, and committee report, S. Rpt. 114-49, are available on congress.gov.
Ranchi : A woman and her year-old daughter were killed after rampaging elephants destroyed their mud house early on Wednesday in Jharkhand’s Hazaribagh district, police said. A herd of elephants entered Uppada village on Tuesday night and started damaging property. Villagers alleged that Forest officials were informed about it but they did not help them. Also Read – National Herald case: Officer bearers of Congress were cheats, Subramanian Swamy tells court Advertise With Us On Wednesday morning, the elephants attacked a house of Raju, who was sleeping with his wife and two children.”When elephants attacked our house, my wife asked me to go outside with the children. I managed to escape with one child but my wife Pano, 30, and one-year-old daughter Golu got buried in the house,” he said. The Police and Forest officials sent the bodies for post-mortem.Over 700 people have been killed by rampaging elephants in Jharkhand so far.
Sweet tributes to Nutella billionaire56 viewsSweet tributes to Nutella billionaire56 views00:00 / 00:00- 00:00:0000:00Sweet tributes to Nutella billionaire56 viewsBusinessHe spent five decades building the Ferrero brand into a global chocolate and confectionary empire. Some called Michele Ferrero a real life Willy Wonka having created Nutella, Kinda Eggs and of courseVentuno Web Player 4.50He spent five decades building the Ferrero brand into a global chocolate and confectionary empire. Some called Michele Ferrero a real life Willy Wonka having created Nutella, Kinda Eggs and of course
Images of regions of interest (colored lines) in the white matter skeleton representation. Data from left and right anterior thalamic radiation (ATR) were averaged. Image courtesy of C. Bouziane et al. September 10, 2013 — In patients with atrial fibrillation, delayed enhancement magnetic resonance imaging (DE-MRI) performed before ablative treatment can stage the degree of damaged heart tissue (atrial fibrosis) and help predict whether treatment will be successful or not, according to results of the Delayed Enhancement — MRI determinant of successful Catheter Ablation of Atrial Fibrillation (DECAAF) trial.”The DECAAF results show that stage of atrial fibrosis prior to ablation is a new, powerful, independent predictor of outcome,” said lead investigator Nasir Marrouche, M.D., from the CARMA Center at the University of Utah in Salt Lake City.”By performing this imaging before ablative treatment we can triage patients according to likelihood of treatment success, and avoid ablative procedures in those patients for whom it is unlikely to work. If a patient has late stage 3 or stage 4 fibrosis their chance of being cured is only 30-35 percent, which is really low, but if they’re in an early stage their chance of cure is 60-80 percent,” he said.The DECAAF trial included 260 atrial fibrillation (AF) patients with atrial fibrosis who were undergoing ablation.The patients, from 15 centers in the United States, Europe and Australia were a mean age of 59 years, and 64.6 percent of them had paroxysmal AF.High resolution Delayed Enhancement MRI (DE?MRI) was performed up to 30 days before ablation in all patients to determine the presence and extent of atrial fibrosis, while post- ablation DE-MRI was performed at 90-days follow-up in 177 of the subjects, to determine the extent of residual ablation.At the 90-day follow-up, recurrence of arrhythmia was noted in 88 of the 260 patients (33.8 percent) based on Holter monitors and electrocardiograms.Multivariate analysis revealed two independent predictors of successful ablation or recurrent symptoms were stage of atrial fibrosis before ablation (P<0.001) as well as residual fibrosis after (P<0.001).Specifically, patients whose pre-ablation fibrosis was stage 1 (defined as less than 10% damaged atrial tissue) had an 85.8% success rate, those with stage 2 (10% - 20% damage) had a 63.3% success rate, those with stage 3 (20% - 30% damage) had a 55% success rate and those with stage 4 (more than 30% damage) had a 31% success rate.For every increased percentage of fibrosis before ablation, there was 6.3% increased risk of recurrent symptoms after ablation (hazard ratio [HR] 1.063), said Marrouche.Similarly, for every percentage of residual fibrosis there was an 8.2 percent increased risk of recurrent symptoms (HR 1.082).A secondary finding of the study, based on post-ablation imaging, showed that the type of ablation clinicians used also had an impact on success rates. The choice of procedure was not dictated in the study protocol and was left to the discretion of individual treating physicians.After comparing pre-ablation images of fibrotic tissue, with post-ablation images showing the extent of residual fibrosis, a surprise finding was that pulmonary vein ablation, which is the standard-of-care in atrial fibrillation ablation candidates, is not the best ablative approach, said Marrouche."We do ablation around the pulmonary veins because we have assumed for years that the trigger for AF comes from the vein — that's the standard of care," he said. "But what we found in DECAAF is that ablation of the veins did not predict outcome. In fact, the most important predictor of outcome, along with stage of atrial fibrosis, was the degree of ablation of the fibrotic tissue. Rather than targeting the pulmonary veins, procedures which ablated fibrotic tissue produced better outcomes - the more that was targeted, the better the outcome."For more information: europace.oxfordjournals.org/content/currentDISCLOSURES: Marrouche disclosed that he has received honoraria from: Biotronik, Siemens, Boston Scientific, and Boehringer Ingelheim; he has received consulting fees from: Sanofi and eCardio; he has received research grants from eCardio and estech; he has received equipment from Siemens; he has stock options with MRI-Intervetions; and holds stock in Marreck Inc. 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CAIRO — Egypt’s powerful military threatened on Monday to step in within 48 hours to resolve the political crisis that has pitted President Mohammed Morsi’s opponents against his supporters over months of protests and clashes that have ground this country to a dangerous standstill.The warning, widely interpreted as a military pledge to stage a coup, stoked fears of violent backlash from Morsi backers and signaled a dark turn in Egypt’s volatile struggle to navigate a path to stable democracy since a popular revolution ended 60 years of authoritarian rule in 2011. A military council ran the country for more than 16 months after the uprising, then retreated to the sidelines as Morsi consolidated power after winning the nation’s first-ever democratic elections one year ago.The commander of Egypt’s armed forces, Abdel Fatah al-Sissi, issued the ultimatum to the government and opposition groups in a televised statement after millions of anti-government protesters over the weekend called for Morsi’s ouster in the largest show of opposition to the president since he took office.The statement did not make clear whether commanders want Morsi to step down or share power, and it did not specify the kind of role the armed forces would assume if the stalemate continued. Instead, Sissi pledged to impose a “roadmap” forward if the situation is not resolved, leaving considerable room for interpretation.“If the demands of the people are not met within the given period of time, [the military] will be compelled by its national and historic responsibilities, and in respect for the demands of Egypt’s great people, to announce a roadmap for the future, and procedures that it will supervise involving the participation of all the factions and groups,” Sissi said, calling the coming two days a “last chance.”Late Monday, after a meeting between Sissi and Morsi, the military published another statement on its Facebook page, denying that it was planning a takeover.“The beliefs and the culture of the Armed Forces do not allow pursuit of a ‘coup’ policy,” the statement said. The military acts only “with the will of the great Egyptian people and their ambitions towards change and reform.”Anti-government activists — some of whom were protesting against the generals last year — have called repeatedly on the military in recent days to back their campaign against Morsi and his supporters in the Islamist Muslim Brotherhood, whom they accuse of hoarding power and failing to enact meaningful economic and political reforms.Many interpreted the military ultimatum as a victory.“I don’t think anyone wants to deal with Morsi anymore,” said Wael Nawara, a political activist and the co-founder of the liberal Dustour party. “So that effectively means that the military will basically appoint some kind of transitional government.”Angry crowds of Morsi supporters swelled in Cairo after the military’s statement, and clashes erupted between the president’s supporters and opponents in several cities. Speaking on the condition of anonymity, an official inside the presidency said Morsi and his advisers were “certainly . . . reading this as a coup statement.”Morsi is unlikely to resign willingly, the official said, warning that Egypt could descend into a civil war similar to Algeria’s in the 1990s, which began after that country’s military usurped power ahead of an imminent Islamist electoral victory.“Everything is possible,” the official said, adding that “certain factions” among the president’s Islamist supporters have been “kind of holding it in, so to speak, in the face of what they perceive to be multiple provocations.”Anti-Morsi protesters, who packed into Cairo’s Tahrir Square for a fourth straight day on Monday, greeted Sissi’s announcement with thunderous cheers. After Sissi, who is also the country’s defense minister, spoke, military helicopters trailing the Egyptian flag flew over Tahrir and downtown Cairo, prompting more celebration.Across the city at the Islamists’ rival sit-in, Brotherhood politicians and supporters took a steadfast posture in the face of Sissi’s perceived threat.“Any coup against legitimacy will not pass, except through our necks,” Mohamed al-Beltagi, a Brotherhood member of Egypt’s now-dissolved lower house of parliament, said from a stage outside Cairo’s Rabia al-Adawiya mosque.Monday is not the first time that Egypt’s top generals have sought to shepherd the nation through a crisis. Egyptians have long been socialized to admire the military, which has remained Egypt’s most popular state institution despite the generals’ management of a rocky transition after President Hosni Mubarak’s ouster in 2011.Mubarak’s top general, Mohammed Hussein Tantawi, then stepped in, earning the military widespread accolades as national saviors. But opposition to military rule, particularly among the youth activists who spearheaded the uprising, mounted last year as reports of arbitrary arrests, torture and closed military trials surfaced.Some observers credited Morsi’s electoral win — against a former military man — as a backlash against months of disappointment under the generals.But anger at the military has faded in a country beset by poverty where a growing number of Egyptians blame a crippling economic crisis on Morsi.On Monday, some prominent Egyptian activists acknowledged that they were wary of a military coup, even though opposition groups had advocated loudly for military intervention. Others argued that there was little choice.“The problem is that our other option is Morsi staying in power,” said Ahmed Maher, the leader of the April 6th youth movement, which helped lead the uprising against Mubarak and later, the protests against military rule.The appointment of Sissi — the youngest member of the body of commanders that ruled Egypt for 16 months after Mubarak’s fall — to the helm of the armed forces came in a shadowy reshuffle that caught many Egyptians by surprise. Sissi was little known in Cairo when Morsi picked him to succeed Tantawi shortly after taking office, prompting speculation in Egypt that Sissi had Islamist leanings.Some analysts warned on Monday that any kind of military interference would send Egypt down a slippery slope. “No matter what happens at this point, the military is going to be intervening very directly in the political process,” said Shadi Hamid, a Middle East expert and the director of research at the Brookings Doha Center.Hamid said he thought the coming days would likely yield a coup or “an effective coup,” whereby the military pressures Morsi into calling early elections. That would set a dangerous precedent, he said, making any future mass protests an opportunity for the military to step in.Speaking from Tanzania before the military statement Monday, President Barack Obama appeared to distance his administration from Morsi’s. “Our commitment to Egypt has never been around any particular individual or party,” he said. “Our commitment has been to a process.”Washington has said it would deal with a democratically elected government in Egypt, the president said, but adding, “Although Mr. Morsi was elected democratically, there’s more work to be done to create the conditions in which everybody feels that their voices are heard and that the government is responsive and truly representative.”Opposition groups called for continued protests Tuesday. The U.S. Embassy in Cairo said it planned to remain closed.Anti-American sentiments have been on the rise in Egypt in recent months. Morsi’s opponents have accused the United States of being party to a conspiracy to keep Morsi in power. The official in Morsi’s office, speaking Monday, had the opposite interpretation, saying that some in the president’s camp believed any possible coup “would not happen without American tacit acquiescence or outright support.”On Friday, an American student from Chevy Chase was stabbed to death while watching clashes between the government’s opponents and supporters in the coastal city of Alexandria.Health officials said that at least 16 people have died in clashes between supporters and opponents of the president since Sunday. Protesters stormed and ransacked the Muslim Brotherhood’s headquarters in the early hours of Monday morning, looting furniture and setting rooms ablaze as police officers looked on.Before the military’s announcement Monday, five of Morsi’s cabinet ministers submitted their resignations in a show of solidarity with the anti-government protesters, the state news wire reported.Washington Post special correspondent Sharaf al-Hourani contributed to this report.© 2013, The Washington Post Facebook Comments No related posts.
February 1, 2017 555 Views Steven MnuchinSteven Mnuchin, President Donald Trump’s nominee for Secretary of the Treasury, moved closer to a full Senate vote on his confirmation after all.Following a second day of protest by Democrats on the Senate Finance Committee, the Republicans on the committee voted to bypass the rules requiring the Democrats to be present for a vote to move a candidate to the next round.The GOP senators voted 14 to zero to advance both Mnuchin and Health and Human Services Secretary nominee Tom Price to the Senate for a final confirmation vote.The Republican members of the Committee used a parliamentary procedure to hold the vote without the participation of the Democratic members.”We took some unprecedented actions today due to the unprecedented obstruction on the part of our colleagues,” Sen. Orrin Hatch, the chair of the committee, said.Hatch on Tuesday called the Democrats’ efforts to stall a vote on Mnuchin “abysmal” and “amazingly stupid,” excoriating them to return and give Mnuchin an up-or-down vote.Sen. Ron Wyden (D-Oregon), the ranking member on the Senate Finance Committee, accused Republicans of “breaking the rules” by holding a vote without Democratic input.”I don’t know all the details of what just transpired, but it seems to me the basic proposition of breaking the rule so that you can in effect look the other way in the face of strong evidence of serious ethical problems for two nominees is exceptionally troubling,” Wyden said.Several Democratic senators said they have concerns over Mnuchin, specifically over the use of “robo-signing” during his tenure at OneWest.“I am pleased that Treasury Secretary nominee Steven Mnuchin will move on to a full Senate vote,” said Ed Delgado, President and CEO of the Five Star Institute and former Wells Fargo and Freddie Mac executive. “However, it is unfortunate that the Senate Finance Committee could not come to this decision unilaterally. If there was ever a time to move forward together as a nation, that time is now.”Paulina Gonzales, executive director of the California Reinvestment Coalition, said she’s opposed Mnuchin’s nomination from the start, saying he intentionally misled the Committee about OneWest’s activities during the housing crisis.“Senator Hatch and the Republicans on the committee sent a clear message to the American public this morning that a presidential nominee need not tell the truth about his record and can still be assured of his nomination being moved forward,” Gonzales said. Voters place our trust in our senators to obtain the truth from presidential nominees about their track records, and in fact, that is the point of confirmation hearings. Yet at Mr. Mnuchin’s hearing, he lied to the senators about his bank’s well-documented history of robo-signing, he refused to provide information about the numbers of foreclosures he had overseen at OneWest Bank, and, amazingly, he continued this obfuscation twice in his follow up written responses to senators.” Government Steven Mnuchin Treasury 2017-02-01 Phil Banker Share GOP Suspends Rules, Advances Mnuchin Vote in Daily Dose, Featured, Government, Headlines, News