The scenario that is presented in the immediate future for the clubs is unknown, but yes a fixed idea is being forged: in the event that the competition returns it will be without fans. The presence of followers in the stands seems ruled out in the coming months and in Oviedo its future will be played without the heat of its followers, one of its most powerful weapons. The blue club, which maintains its position of not playing without followers, is already thinking of alternatives to try to wink at its fans. As reported by the club, three possibilities have been evaluated to try to make fans carry football as well as possible without the stands full. The three ideas are under evaluation, pending different scenarios. The first is to create a sort of drive-in on the outskirts of the Tartiere to which the members can go and follow, at the same time as they play, the league clash, always inside the cars.Another possibility is to screen print the name of the team’s subscribers on a commemorative shirt. although it would not be possible for the remaining 11 days since new clothes cannot be used. The club values as possibilities to offer members the next anniversary jacket or use another one, such as the thermal used in warm-ups before the game.The third option devised in the Carbayona entity is for the next campaign and under the budget that it is not possible to go to the stadiums during the beginning of the competition. In that scenario, the club would try to reach an agreement with a television platform that owns the Second Rights so that the members can obtain a subscription with which they can follow only Oviedo’s matches.
Source:http://www.fv-berlin.de/news/the-dark-side-of-our-genes-2013-healthy-ageing-in-modern-times May 21 2018The transition to modernity – largely driven by the Industrial Revolution – provided us with easier access to food and clean water, with antibiotics, vaccines, and modern medicine. Yet modernity did not just bring fewer infectious diseases and longer life: it also created an environment radically different from the one we evolved in. Genes helpful in our evolutionary past may now predispose us to chronic disease – such as cardiovascular diseases and cancer – in old ages. In a paper published in the journal Nature Reviews Genetics an international team of five scientists collate the evidence for this mismatch between past evolutionary adaptation and our modern lives. They also ask whether natural selection linked to modernization might reduce globally the burden of some chronic diseases.Over the last four centuries human ecology, life styles and life histories have dramatically changed. The transition to modernity also altered the major causes of human death. Infectious diseases prevalent in childhood have given way to chronic diseases associated with aging. Naturally – as all of us must die – if some causes of death decrease others must increase in proportion. However, the increasing differences between the circumstances our genes have adapted to and our new environment also plays an important role.Aging is, in part, caused by the combined effect of many genes that are beneficial when young, but have adverse effects at older ages. Genes can influence a variety of traits and can also express themselves differently as we age (pleiotropy). The term antagonistic pleiotropy describes genes that can carry both beneficial and detrimental effects. Somewhat counter-intuitively evolution by natural selection can lead to antagonistic pleiotropy spreading in populations: The benefits received when young can outweigh the evolutionary disadvantages in old age. Some variants of the gene BRCA1 are, for example, beneficial to fertility. However, women who carry one of such variants of BRCA1 will – more likely than not – develop breast cancer by the age of 90.”Angelina Jolie’s decision to opt for a preventive double mastectomy instead of risking breast cancer was based on her carrying a high-risk BRCA1 variant,” Virpi Lummaa, professor at the University of Turku in Finland, explains. “This gene variant hasn’t been eliminated by natural selection in the past, precisely because it also has a great benefit for female fertility. Nowadays, the situation is much worse. Due to our much lower fertility levels and longer lifespans the early benefits of such genes no longer play out.””It is clear that some mutations that benefit fertility have been favored by natural selection despite heavy costs in old age. It seems likely that these genes have contributed to the rise in chronic disease in modern societies, but it’s still uncertain if these genes are the main cause of that increase or just a minor contributing factor,” says Jacob Moorad, from the University of Edinburgh.Related StoriesCoffee, sugary drinks, or alcohol? It’s in your genes.Gene modulation goes wireless hacking the “boss gene”Nanoparticles used to deliver CRISPR gene editing tools into the cellIn contrast, the evolutionary impact of contemporary life on human health is difficult to establish: evolutionary change often requires many generations to leave an unambiguous trace in our genome. The review found “suggestive but not yet overwhelming” evidence that natural selection, the engine of evolution, is changing course in our modern times. Several studies in pre- and post-industrial populations point, for example, to a selection toward an extended fertility period in women.”We have to be cautious here, though,” says Stephen Stearns, professor at Yale University in the USA. “Changes in human biology are driven by two non-exclusive processes. The environment directly impacts how our genes are expressed: Bad nutrition in childhood can cause, for example, stunted growth. But the environment also shapes natural selection. Natural selection can make some genes more – and others less – frequent in the population over time: Lactose-intolerance in adults, for example. It’s tempting to point to natural selection when we observe a particular change. However, particularly when the changes occurred recently, it is more likely that gene expression has changed, rather than that the genes themselves have adapted to a new environment.””Future studies and methodological development can help us clarify the extent to which chronic disease and genetic expression are linked and whether natural selection begins to counteract the increased burden of chronic disease. It is absolutely essential to establish large multigenerational cohort studies to create clear evidence”, explains Stephen Corbett, Director of the Centre for Population Health at the Western Sydney Local Health District in Australia.Alexandre Courtiol, scientist at the Leibniz Institute for Zoo and Wildlife Research (IZW) in Berlin Germany, and co-author of this study adds: “Yes, genes are guilty but waiting for natural selection to adapt our great-great-great-grandchildren to our modern environment is inefficient. It may also not work since the modern environment changes at very high pace. The more rational response to the increase in chronic disease is to change our social environment and our lifestyles in ways that better suit us. We all know the recipe: sleep more, eat less junk, be regularly active and pollute less. True, this is difficult to implement but hopefully not impossible.”